Advanced LC/MS/MS Methods for Monitoring PPCPs in Waters

Contaminants of emerging concern (CECs) include a wide range of individual and classes of chemicals.  Monitoring CECs is essential in wastewater reclamation because the potential impacts of CECs on aquatic life and humans are largely unknown. In particular, indirect potable reuse (IPR) and direct potable reuse (OPR) have become a viable option to meet increasing municipal drinking water supply requirements in certain geographical locations in which water scarcity is an increasing problem due to growing demand for water and climate change.

Commonly monitored CECs include pharmaceuticals and personal care products (PPCPs), veterinary drugs, steroids and hormones, endocrine disrupting chemicals (EDCs), alkylphenols flame retardants, explosives, cyanotoxins, household cleaning products, organochlorine pesticides, per- and polyfluoroalkyl substances (PFAS), bisphenol A, N-nitroso-dimethylamine, 1,4-dioxane, 1,2,3-trichloropropane, trichloroethylene, perchlorate, tungsten, nanomaterials, etc.. A variety of analytical techniques have been used for monitoring different CECs, which primarily include LC/MS/MS, GC/MS, and HRGC/HRMS combined with solid-phase extraction (SPE), liquid-liquid extraction (LLE), and/or derivatization. 

This webinar will first provide a review of various analytical methods used for CECs.  Secondly, this webinar will introduce new direct injection LC/MS/MS methods with isotope dilution analysis for suitable PPCPs.  The direct injection analysis methods can provide a few advantages over the conventional SPE and LLE methods.  The advantages may include applicability of monitoring more PPCPs, faster availability of sample results, better data accuracy, and lower analytical costs in some cases.

Original Airdate:  Tuesday, January 16, 2024
 
Length:  60 minutes 

Presenter: Yongtao (Bruce) Li & Andy Eaton - Eurofins Drinking Water Testing