In-Vivo

In Vivo Sunscreen Testing: Ensuring Efficacy and Safety for Human Skin

At Eurofins CRL, we understand the importance of protecting human skin from the harmful effects of sunlight, such as sunburn, pigmentation, wrinkles, dermatitis, and premature aging. Our comprehensive range of in-vivo sunscreen testing services is designed to meet global regulatory guidelines, ensuring the efficacy and safety of sunscreen formulations for unprotected human skin.

Static SPF Testing

SPF measurement is performed on a panel of at least 10 human adult volunteers, chosen for diverse skin types, providing valuable insights into Sun Protection Factor (SPF) efficacy and protection against harmful UV rays.

• FDA Compliance: Stay ahead in FDA compliance as sunscreen regulations evolve. Eurofins CRL keeps you informed about the ongoing ruling changes to ensure your product aligns with the latest standards for sunscreen manufacturers.
• ISO 24444: Our testing complies with ISO 24444, providing an in vivo determination of sunscreen SPF according to international standards. We adapt swiftly to regulatory changes, incorporating them into our protocols to meet the requirements of the international standard.

Water Resistant Testing

The water resistance test indicates that a sunscreen product’s labeled SPF protection is retained for a certain period of time after immersion into circulating water, ensuring reliable protection even in water-based activities. The determination of a water-resistant claim is performed by standardized and reproducible methods meeting FDA, ISO, and AS/NZS guidelines.

Types of water resistance testing available are as follows

• FDA 40min/80min
• ISO 40min/80min
• AS/NZS 40min/2hr/4hr

Sweat Resistant Testing

Similar to Water Resistance SPF testing, Sweat Resistance testing takes place in our custom-built environmentally controlled chamber. Here we can adapt various means of activity to induce sweating to evaluate the “staying power” of a particular SPF formulation under various exercise and environmental conditions, ensuring reliable protection for active individuals.

Wet Skin Application Testing

Wet Skin Application testing is conducted by lightly spraying water onto the test site prior to test product applications, simulating real-world scenarios where sunscreen is applied to wet skin. UV exposures are then administered to the test products per the requested testing methodology, followed by an SPF or UVAPF value determination, providing insights into the effectiveness of sunscreen application on wet skin. This application technique can be added to all FDA, ISO, and AS/NZS testing methods.

Sand Resistance Testing

Sand Resistance testing is conducted by applying and removing sand from test products to simulate the action of being on the beach. UV exposures are then administered to the test products per the requested testing methodology, followed by an SPF or UVAPF value determination. This resistance testing can be added to all FDA, ISO, and AS/NZS testing methods, ensuring reliable protection even in sandy environments.

Trust Eurofins CRL's expertise in in-vivo sunscreen testing to ensure your product's efficacy and safety for human skin. Contact us today to learn more about our comprehensive testing services and how we can help you meet global regulatory requirements.

Whitecast Testing

Our experts will design a study protocol to demonstrate your SPF product's ability to avoid whitecast on the skin after application.

Phototoxicity/Photoallergy testing

The objective of this study is to evaluate the potential of a test material to elicit a phototoxic and/or photoallergic response. Does the test product cause any irritation or an allergic reaction after being exposed to the solar spectrum?