Weight Management and Themogenic Ingredients

The first step to ensuring the safety of diet pills, nutritional supplements and weight loss products, while also achieving compliance with the dietary supplement cGMPs, is confidence in product composition.

Below is an overview of weight loss and thermogenic active ingredients found in a large number of non-prescription weight management product formulations.

• Camellia sinensi, Green tea catechins including epigallocatechin gallate (EGCG) by HPLC

• Garcinia cambogia , Hydroxycitric Acid (HCA) by HPLC or CE

• Chromium by ICP or ICP/MS

• Bitter Orange, Synephrine (oxedrine) by HPLC or CE

• Octopamine by HPLC or CE

• Methyl xanthines (caffeine, theobromine, theopholine) by HPLC

• 7-Keto (3-acetyl-7-oxo-dehydroepiandros-terone) by HPLC

• Capsicum sp. capsaicin and dihydrocapsaicin by HPLC

• Coleus forskohlii, forskolin by HPLC

• Yohimbine by HPLC

• Commiphora wightii resin, Guggulsterones (guggul lipids) (sum of Z & E isomers) by HPLC

• Salicylates by HPLC

• Evodia rutaecarpa, evodiamine by HPLC

Eurofins offers testing methods for these ingredients that are suitable for both raw materials and finished dosage forms. Most can be tested by either high performance liquid chromatography (HPLC) or capillary electrophoresis (CE), and compendia methods are also available, where appropriate. To comply with the supplement cGMPs Eurofins has developed the methods and preparation procedures that will be appropriate for the sample matrix.

Eurofins has over 20 years of experience in the nutritional supplement industry, giving us unique expertise in handling raw materials, extracts, hard-shell split capsules, tablets, soft gelatin capsules, drinks and powders. To obtain additional information and pricing, please contact us here.